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. 2020 Oct 22;8(11):E1611–E1622. doi: 10.1055/a-1240-0027

Table 2. Pooled performance of CS and LBC techniques.

Malignant Benign Suspicious
Pooled odds ratio (95 % confidence interval)
Conventional smear vs Liquid based cytology (LBC) NA OR = 1.1 (0.7–1.75) P  = 0.7 I 2  = 2; 8 studies OR = 1.23 (0.96–1.59) P  = 0.1 I 2  = 76; 5 studies
Conventional smear vs Precipitation-LBC (SurePath) OR = 0.39 (0.19–0.8) P  = 0.01 I 2  = 60; 3 studies OR = 1.1 (0.6–2.1) P  = 0.7 I 2  = 48; 3 studies -NA-
Conventional smear vs Filtration-LBC (ThinPrep, CellPrep) OR = 1.69 (1.02–2.79) P  = 0.04 I 2  = 56; 7 studies OR = 1.1 (0.54–2.17) P = 0.8 I 2  = 0; 5 studies OR = 0.47 (0.27–0.8) P  = 0.006 I 2  = 0; 4 studies
Pooled proportions (95 % confidence interval)
Conventional smear 64.9 % (43.4–81.7) I 2  = 96; 10 studies 26.4 % (8.2–58.8) I 2  = 94; 8 studies 22.8 % (10.4–42.7) I 2  = 93; 5 studies
Liquid-based cytology subtypes
Precipitation-LBC (SurePath) 84.1 % (50.9–96.4) I 2  = 98; 3 studies 23.2 % (3.3–72.5) I 2  = 98; 3 studies NA
Filtration-LBC (ThinPrep) 48.6 % (24.2–73.7) I 2  = 84; 7 studies 29.1 % (6.7–70.3) I 2  = 85; 5 studies 27.5 % (11.9–51.5) I 2  = 18; 4 studies

CS convetional smear; LBC, liquid-based cytology.