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. Author manuscript; available in PMC: 2021 Feb 5.
Published in final edited form as: Nature. 2020 Aug 5;586(7830):567–571. doi: 10.1038/s41586-020-2622-0

Extended Data Figure 4. mRNA-1273 elicits robust pseudovirus neutralizing antibody responses to SARS-CoV-2_D614G.

Extended Data Figure 4.

BALB/c mice (n=8/group) were immunized at weeks 0 and 3 weeks with 1 μg (red) of mRNA-1273, in three individual studies, or PBS (n=5). Sera were collected 2 weeks post-boost and assessed for neutralizing antibodies against homotypic SARS-CoV-2_D614 pseudovirus (filled circles) or SARS-CoV-2_D614G (unfilled circles). Comparisons between D614 and D614G were made by two-sided Mann-Whitney test within each study, and no significance was detected. Data are presented as GMT +/− geometric SD.