Table 1 |. Pathogenic mutations in melanocytes from normal human skin.

A curated list of pathogenic mutations in melanocytes found in this study (see methods for details on how they were defined). BCC = Basal Cell Carcinoma, Mel = Melanoma.

Pathway	Hugo Symbol	Protein Change	Donor	Site
MAPK	BRAF	p.G466R	Donor6	Back (adjacent to a BCC)
	BRAF	p.G466R	Donor6	Back (adjacent to a Mel)
	BRAF	p.D594G	Donor6	Back (adjacent to a Mel)
	BRAF	p.D594G	Donor6	Back (adjacent to a Mel)
	BRAF	p.D594G	Donor13	Back (adjacent to a Mel)
	BRAF	p.D594G	Donor13	Back (adjacent to a Mel)
	BRAF	p.D594G	Donor13	Back (adjacent to a Mel)
	CBL	p.H398L	Donor4	Shin
	CBL	p.H398L	Donor4	Shin
	MAP2K1	p.E203K	Donor4	Shoulder
	MAP2K1	p.E203K	Donor10	Thigh
	NF1	p.W1314*	Donor6	Back (adjacent to a BCC)
	NF1	p.P1847L	Donor13	Back (adjacent to a Mel)
	NF1	p.Q2239*	Donor13	Back (adjacent to a Mel)
	NF1	p.R1276*	Donor6	Back (adjacent to a Mel)
	NF1	p.V2511fs	Donor10	Back
	RASA2	p.L83I	Donor6	Back (adjacent to a BCC)
	RASA2	p.P376S	Donor13	Back (adjacent to a Mel)
	RASA2	p.P376S	Donor13	Back (adjacent to a Mel)
	NRAS	p.Q61L	Donor13	Back (adjacent to a Mel)
Cell Cycle	CDKN2A	p.V43M	Donor6	Back (adjacent to a BCC)
	PPP6C	p.R264C	Donor10	Back
Epigenetic	ARID2	p.E1670K	Donor7	Cheek
	ARID2	p.Q1591*	Donor4	Buttock
	ARID2	p.A18V	Donor6	Back (adjacent to a Mel)
	ARID2	p.L202S	Donor6	Back (adjacent to a Mel)
	ARID2	p.P1392L	Donor13	Ear
PI3K	PTEN	p.QYPFEDH87fs	Donor13	Ear
RNA Processing	DDX3X	p.P167L	Donor13	Back (adjacent to a Mel)