Table 4. Linear Regression Model for MacrophageMediated Cholesterol Efflux Capacity.

Two models were used to evaluate the relation between the cholesterol efflux capacity and stroke in 24 h poststroke intervention samples compared with nonstroke controls. Both models adjust for multiple patient covariates which may affect cholesterol efflux capacity.

	Dependent variable:
	Cholesterol efflux capacity
	(1)	(2)
Stroke status	−3.435 (−5.330, −1.540)	−2.447 (−4.329, −0.565)
	p = 0.001***	p = 0.014**
Sex (male)		1.708 (0.014, 3.402)
		p = 0.053*
Age at blood collection		0.002 (-0.093, 0.096)
		p = 0.971
High-density lipoprotein cholesterol	0.076 (0.031, 0.121)	0.088 (0.043, 0.132)
	p = 0.002***	p = 0.0003***
Low-density lipoprotein cholesterol		0.030 (0.015, 0.045)
		p = 0.0003***
Constant	10.717 (7.619, 13.815)	4.217 (-3.706, 12.139)
	p = 3.7E-09***	p = 0.302
Observations	70	65
R2	0.409	0.53
Adjusted R2	0.391	0.49
Residual Std. Error	3.521 (df = 67)	3.001 (df = 59)
F Statistic	23.172*** (df = 2; 67)	13.299*** (df = 5; 59)

Model 1 adjusts for HDL-C; Model 2 adjusts for HDL-C, LDL-C, sex, and age. HDL indicates high-density lipoprotein; and LDL, low-density lipoprotein.