Table 3.

Associations Between Neuronal Injury Markers (GFAP, Tau, UCHL-1) and Postoperative Delirium

		Delirium			Delirium			Delirium
GFAP (pg/ml)		OR (95% CI)	Tau (pg/ml)		OR (95% CI)	UCHL-1 (pg/ml)		OR (95% CI)
PREOP (n=53 matched pairs)			PREOP (n=53 matched pairs)			PREOP (n=52 matched pairs)
Q1	≤164.24	Reference	Q1	≤1.85	Reference	Q1	≤12.24	Reference
Q2	164.25–225.41	1.78 (0.54–5.87)	Q2	1.86–2.71	3.30 (0.93–11.75)	Q2	12.25–18.84	1.14 (0.36–3.71)
Q3	225.42–333.04	2.03 (0.60–6.94)	Q3	2.72–4.50	1.81 (0.63–5.24)	Q3	18.85–34.45	1.96 (0.57–6.66)
Q4	≥333.05	2.97 (0.72–2.20)	Q4	≥4.51	2.22 (0.78–6.32)	Q4	≥34.46	1.39 (0.46–4.20)
p for trend		0.14	p for trend		0.29	p for trend		0.54
POD2 (n=44 matched pairs)			POD2 (n=44 matched pairs)			POD2 (n=48 matched pairs)
Q1	≤174.14	Reference	Q1	≤2.15	Reference	Q1	≤19.93	Reference
Q2	174.15–243.49	0.93 (0.29–2.97)	Q2	2.16–3.26	0.86 (0.30–2.48)	Q2	19.94–31.35	0.75 (0.22–2.60)
Q3	243.50–385.18	1.05 (0.31–3.58)	Q3	3.27–5.33	2.28 (0.62–8.45)	Q3	31.36–64.74	1.24 (0.37–4.19)
Q4	≥385.19	2.19 (0.56–8.53)	Q4	≥5.34	0.91 (0.32–2.60)	Q4	≥64.75	2.17 (0.63–7.44)
P for trend		0.25	P for trend		0.68	P for trend		0.19

Abbreviations: GFAP=glial fibrillary acidic protein, POD2=postoperative day 2, PREOP=preoperative, Q=quartiles, UCHL-1 = ubiquitin carboxyl-terminal hydrolase L1, Q=quartile