Table 3.
Clinical characteristics, echocardiography, 24 h Holter-ECG and 24 h-blood pressure monitoring findings in patients with primary (PAI) and secondary adrenal insufficiency (SAI)
| PAI patients (n = 11) | SAI patients (n = 6) | |
|---|---|---|
| Clinical characteristics | ||
| Age (years) | 45.0 (18.0–65.0) | 49.0 (42.0–67.0) |
| BMI (kg/m2) | 24.4 (19.8–31.2) | 26.1 (20.1–32.8) |
| Hypertension (%) | 0 | 0 |
| Diabetes mellitus (%) | 1 (9) | 0 |
| Glycaemia (mg/dL) | 77 (60–159) | 84 (67–91) |
| Total cholesterol (mg/dL) | 202 (152–284) | 220 (177–321) |
| LDL-cholesterol (mg/dL) | 119 (70–174) | 143 (99–223) |
| Triglycerides (mg/dL) | 114 (59–273) | 179 (77–253) |
| s-Na (mmol/L) | 139.0 (132.0–145.0) | 140.5 (134.0–143.0) |
| s-K (mmol/L) | 4.3 (4.0–5.1) | 3.9 (3.6–10.9) |
| Echocardiography | ||
| IVSTDd (mm) | 8.5 (7.0–10.0) | 9.2 (7.3–11.7) |
| LVEDd (mm) | 45.9 (42.1–53.0) | 49.8 (43.3–56.0) |
| LAD (mm) | 34.0 (30.0–37.0) | 38.0 (23.0–44.0) |
| LVEF (%) | 64.5 (50.0–68.7) | 64.5 (55.0–76.0) |
| Holter-ECG | ||
| HR day (bpm) | 82 (72–96) | 74 (67–85) |
| HR night (bpm) | 74 (65–90) | 64 (58–80) |
| 24 h-blood pressure | ||
| MAP-S day (mmHg) | 119 (96–138) | 129 (106–132) |
| MAP-D day (mmHg) | 72 (64–87) | 79 (74–89) |
| MAP-S night (mmHg) | 100 (94–124) | 111 (91–143) |
| MAP-D night (mmHg) | 63 (54–86) | 67 (59–86) |
Data are presented in median (range) or n (%)
BMI body mass index, bpm beats per minute, HR heart rate, IVSTDd interventricular septum thickness at diastole, LAD left atrial diameter, LVEDd left ventricular end-diastolic diameter, LVEF left ventricular ejection fraction, MAP-D mean arterial pressure-diastolic, MAP-S mean arterial pressure-systolic, S-Na serum Natrium level, s-K serum Kalium level