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. 2020 Jul 28;7(4):261–269. doi: 10.1007/s40801-020-00207-6

Table 2.

ALK inhibitor sequences and proportions of patients

n (%) of overall population (N = 410)
1 ALK inhibitor 233 (56.8)
 Crizotinib only 205
 Alectinib only 20
 Ceritinib only 5
 Brigatinib only 3
2 ALK inhibitors 144 (35.1)
 Crizotinib → ceritinib 59
 Crizotinib → alectinib 21
 Crizotinib → brigatinib 3
 Alectinib →  crizotinib 60
 Alectinib → brigatinib 1
3 ALK inhibitors 31 (7.6)
 Crizotinib → alectinib →  ceritinib 23
 Alectinib → crizotinib →  brigatinib 6
 Ceritinib → crizotinib →  brigatinib 2
4 ALK inhibitors 2 (0.5)
 Alectinib → crizotinib →  brigatinib →  ceritinib 2

ALK anaplastic lymphoma kinase