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. 2020 Oct 9;10:588530. doi: 10.3389/fonc.2020.588530

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Copyright © 2020 Wu, Wang, Yang, Wang, Yang, Liu and Sun.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Correlations among serine hydroxymethyltransferase (SHMT2), programmed cell death-ligand 1 (PD-L1), CKLF-like MARVEL transmembrane domain containing 6 (CMTM6), V-type immunoglobulin domain-containing suppressor (VISTA), B7-H4, Slug, and CD317 in the oral squamous cell carcinoma (OSCC) microenvironment. (A) Representative hematoxylin–eosin and immunohistochemical staining of SHMT2, PD-L1, CMTM6, VISTA, B7-H4, Slug, and CD317 in OSCC. The scale bar represents 50 μm. (B) Strongly positive correlations among SHMT2, PD-L1, CMTM6, VISTA, B7-H4, Slug, and CD317 in OSCC shown by hierarchical clustering. The color scale represents the levels of histoscores.