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. 2020 Oct 22;10:18099. doi: 10.1038/s41598-020-75197-0

Figure 3.

Figure 3

Pathway annotation analysis of AVNFH patient bone tissue proteomics. (A) Reactome pathways showing defects in Cobalamin metabolism, Scavenging heme from plasma, Megaloblastic anemia, Platelet degranulation pathways. (B) WikiPathways showing vitamin B12 and folate metabolism. (C) KEGG pathways showing complement and coagulation cascade pathway. (D) Pathway annotation analysis of AVNFH metabolomics showing significant pathways of patient targeted plasma metabolomics, significant pathways of patient non targeted plasma metabolomics and significant pathways of patient bone trabeculae metabolomics.