Table 1.
Incubation/stimulation solution | Stationary conditions | Stimulation conditions (15 s) | Wilcoxon test (p) | ||||
---|---|---|---|---|---|---|---|
Parameter | R (Ω*cm2) | PD (mV) | PDmin (mV) | PDmax (mV) | PD vs. PDmin | PD vs. PDmax | PDmin vs. PDmax |
RH (n = 70) | |||||||
Median | 844 | − 0.25 | − 0.15 | 0.15 | 0.253 | 0 | 0 |
Lower quartile | 438 | − 0.66 | − 0.95 | − 0.12 | |||
Upper quartile | 1360 | 0 | 0 | 0.7 | |||
A (n = 66) | |||||||
Median | 1024 | − 0.31 | − 0.45 | 0 | 0 | 0 | 0 |
Lower quartile | 740 | − 1.04 | − 1.27 | − 0.94 | |||
Upper quartile | 1563 | 0.18 | − 0.09 | 0.69 | |||
B (n = 72) | |||||||
Median | 894 | − 0.23 | − 1.16 | 0 | 0 | 0 | 0 |
Lower quartile | 610 | − 1.9 | − 2.32 | − 1.77 | |||
Upper quartile | 1136 | 0.12 | 0 | 0.37 | |||
Mann–Whitney test (p) | |||||||
RH vs. A | 0.013 | 0.585 | 0.025 | 0.028 | |||
RH vs. B | 0.929 | 0.238 | 0.001 | 0.001 | |||
A vs. B | 0.007 | 0.142 | 0.062 | 0.119 |
RH isoosmotic Ringer solution, A inhibited sodium transport by amiloride (0.1 mM), B inhibited chloride transport by bumetanide (0.1 mM), PD transepithelial potential difference of epithelial skin surface measured in stationary conditions (mV), PDmin minimal transepithelial potential difference during 15 s stimulation of epithelial skin surface (mV), PDmax maximal transepithelial potential difference during 15 s stimulation of epithelial skin surface (mV), R resistance measured in stationary conditions (Ω*cm2), italic values indicate a level of significance p < 0.05.