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. 2020 Oct 22;10:18094. doi: 10.1038/s41598-020-75275-3

Table 1.

Values of analyzed parameters of skin specimens.

Incubation/stimulation solution Stationary conditions Stimulation conditions (15 s) Wilcoxon test (p)
Parameter R (Ω*cm2) PD (mV) PDmin (mV) PDmax (mV) PD vs. PDmin PD vs. PDmax PDmin vs. PDmax
RH (n = 70)
Median 844 − 0.25 − 0.15 0.15 0.253 0 0
Lower quartile 438 − 0.66 − 0.95 − 0.12
Upper quartile 1360 0 0 0.7
A (n = 66)
Median 1024 − 0.31 − 0.45 0 0 0 0
Lower quartile 740 − 1.04 − 1.27 − 0.94
Upper quartile 1563 0.18 − 0.09 0.69
B (n = 72)
Median 894 − 0.23 − 1.16 0 0 0 0
Lower quartile 610 − 1.9 − 2.32 − 1.77
Upper quartile 1136 0.12 0 0.37
Mann–Whitney test (p)
RH vs. A 0.013 0.585 0.025 0.028
RH vs. B 0.929 0.238 0.001 0.001
A vs. B 0.007 0.142 0.062 0.119

RH isoosmotic Ringer solution, A inhibited sodium transport by amiloride (0.1 mM), B inhibited chloride transport by bumetanide (0.1 mM), PD transepithelial potential difference of epithelial skin surface measured in stationary conditions (mV), PDmin minimal transepithelial potential difference during 15 s stimulation of epithelial skin surface (mV), PDmax maximal transepithelial potential difference during 15 s stimulation of epithelial skin surface (mV), R resistance measured in stationary conditions (Ω*cm2), italic values indicate a level of significance p < 0.05.