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(A) Ribbon diagram of the actin molecule with space filling ATP (protein data bank [PDB]: 1ATN). N, amino terminus; C, carboxyl terminus. Numbers 1, 2, 3, and 4 label the four subdomains (re-printed from Pollard et al. (2016) with copyright permission from Elsevier Publishers). (B) Model of actin protofilaments derived from linear polymers along a single strand of F-actin.
