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Picture cartoon of actin treadmilling, showing that the rate of treadmilling is regulated by ADF/cofilins and profilin, which results in an increase and decrease in the size of actin filaments, respectively. It further shows that Arp2/3 complex nucleate new filaments by its binding with actin monomers and the side of actin filaments, while formins nucleate new filaments by binding actin monomers and through cooperation of profilin.
