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. 2020 Oct 9;14:558987. doi: 10.3389/fnbot.2020.558987

Figure 8.

Figure 8

Insulation deterioration and tip cracking. (A) Side view of a typical electrode with intact platinum [tip], cracked parylene [shaft], and substantial fibrosis, scale 20 μm. (B) Top view of another typical electrode with intact platinum and thick, uniform fibrosis encapsulation, scale 10 μm. (C) An electrode tip with thick encapsulation tissue, scale 3 μm. (D) Detail of cracked platinum tip, scale 200 μm. (E) Delaminating parylene interface, scale 1 μm. (F) Detail of parylene delamination, scale 200 nm. Figure and caption reproduced with permission from Barrese et al. (2016). © IOP Publishing. All rights reserved. Tip cracking and insulation deterioration are irreversible, but potentially compensable with algorithmic approaches.