Table 3.
Oxidation of glycerol with H2O2 catalyzed by [Fe(L)3](OTf)2 with conventional heatinga.
| Entry | L | T (°C) | [H2O2]/[sub] | Conv. (%) | Yields FA (%) | GA (%) | DHA (%) |
|---|---|---|---|---|---|---|---|
| 1 | bpy | 25 | 2 | 2 | – | – | 2 |
| 2 | bpydeg | 25 | 2 | 2 | – | – | 2 |
| 3 | bpy | 40 | 1 | 3 | – | – | 3 |
| 4 | bpy | 40 | 2 | 19b | 16 | <1 | 3 |
| 5 | bpydeg | 40 | 2 | 18 | 17 | – | <1 |
| 6 | bpy | 60 | 1 | 22b | 18 | <1 | 4 |
| 7 | bpy | 60 | 2 | 44b | 33 | 4 | 7 |
| 8 | bpydeg | 60 | 2 | 54b | 43 | 5 | 6 |
| 9c | bpy | 60 | 2 | 56b | 45 | 4 | 7 |
| 10 | bpy | 80 | 2 | 48b | 37 | 3 | 7 |
a
Experimental conditions: [Fe]= 1.5 × 10−2 M; [sub]/[Fe] = 50; H2O2(aq) 30%; t = 30 min; solvent = water. FA, formic acid; DHA, dihydroxyacetone; GA, glycolic acid.
b
Also formed hydroxypyruvic acid <1%.
c
cocat = Hpic; [Hpic]/[Fe] = 5.