Table 2C.
Cross-sectional correlations between cognitive functioning and dynamic functional connectivity between RSNs in PD.
| Cognitive tests | R2 | RSN interactions involved | Unstandardized Beta | Standardized Beta | p-value |
|---|---|---|---|---|---|
| Executive tests | 0.323 | ||||
| DAN-VAN | −18.815 | −0.471 | 0.007* | ||
| DGM-DMN | 10.399 | 0.294 | 0.098 | ||
| DGM-FPN | 14.185 | 0.383 | 0.049* | ||
| Motor perseveration | 0.140 | ||||
| DAN-FPN | −19.57 | −0.401 | 0.053 | ||
| DAN-SMN | −11.93 | −0.294 | 0.030* | ||
| DAN-DGM | 17.80 | 0.358 | 0.080 |
Linear hierarchical regression analyses were performed with a backward elimination method per cognitive outcome measure, corrected for age, sex, education, disease duration, and LEDD. Selection of functional connectivity interactions between RSNs was based on RSNs deemed to be important based on Table 2A. Note that multiple functional connections were tested within the same regression model. R2 values are displayed in the second column as a single value for each separate regression model.