Fig. 1.
Distribution of GT expression in MIBC patients and significant correlations with clinicopathological parameters.
(A) Overall mRNA expression in the entire population of MIBC patients (n = 105) shows that POFUT1 expression was lower than expression of EXT1 and B4GALT1 (p ≤ 0.0001). Since 95% of the MGAT5B signals were below the limit of detection or not detectable, expression of this gene could not be further analyzed. (B; C) EXT1 (p = 0.0276) and B4GALT1 (p = 0.0383) expression were reduced in the male than in the female patients. (D) With regard to the age of the patients, B4GALT1 expression was lower among patients under 70 years of age than those over 70 (p = 0.0016). TaqMan qRT-PCR data were normalized to CALM2 by 40-∆CT and plotted on the Y-axis. Mean and standard deviations are indicated in the scatter plots. Significances were calculated using the Kruskal-Wallis-Test and considered significant if p < 0.05.