Fig. 2.

Kaplan-Meier prediction of GT mRNA expression in MIBC patients.

Normalized qRT-PCR data of GT mRNA expression are plotted as Kaplan-Meier curves in relation to the patients' survival probabilities. Cut offs were determined by partition with a minimal group distribution of ≥25%. Overall survival (OS), cancer-specific survival (CSS), and disease-free survival (DFS) were predicted by log-rank test and considered significant if p < 0.05. As the graphs show, in each case, reduced mRNA gene expression predicted poor probability of survival for MIBC patients. POFUT1 and EXT1 were significant for OS (POFUT1 p = 0.0014; EXT1 p = 0.0150), CSS (POFUT1 p = 0.0007; EXT1 p = 0.0130), and DFS (POFUT1 p = 0.0088; EXT1 p = 0.0286). B4GALT1 was significant for CSS (p = 0.0134) and DFS (p = 0.0493).