Table 2.
Genes for other neuromodulators of motivated behaviors that differ in VTA in the Low and High Dopamine groups.
Gene ID | Gene | Function | Group diff. | p value |
---|---|---|---|---|
HDC | Histidine decarboxylase | Enzyme, catalyzes histamine production | High > Low | 0.004 |
HNMT | Histamine N-methyltransferase | Enzyme, inactivates histamine | High > Low | 0.005 |
VIP | Vasoactive intestinal peptide | Neuropeptide | High > Low | 0.006 |
MC4R | Melanocortin 4 Receptor | Melanocortin receptor | High > Low | 0.016 |
MTNR1B | Melatonin Receptor 1B | Melatonin receptor | High > Low | 0.036 |
NPY5R | Neuropeptide Y Receptor Y5 | NPY and peptide YY receptor | High > Low | 0.040 |
MC3R | Melanocortin 3 Receptor | Melanocortin receptor | High > Low | 0.042 |
HRH1 | Histamine Receptor H1 | Histamine receptor | Low > High | 0.007 |
HTR1B | 5-Hydroxytryptamine Receptor 1B | Serotonin receptor | Low > High | 0.011 |