Table 1.
Demographics and clinical parameters of participants at hospital admission and in-hospital treatment. Data are presented as mean (SD) unless otherwise indicated.
| Characteristic | COVID-19 patients (n=20) |
|---|---|
| Age, years | 55(15) |
| Males, n (%) | 17 (85.0) |
| BMI, kg/m2 | 24.1 (5.2) |
| Current or ex-smoker, n (%) | 8(40) |
| SARS-CoV-2 positive swab, n (%) | 20 (100.0) |
| Duration of hospitalisation, days | 17.7 (11.5) |
| Gas exchange | |
| Respiratory rate, breaths/min | 28(8) |
| SpO2, % | 91(3) |
| pH | 7.44 (0.02) |
| PaO2, mmHg | 87 (37.2) |
| PaCO22, mmHg | 41 (6.2) |
| PaO2/FiO2, mmHg | 283(106) |
| PaO2/FiO2 severity, n (%) | |
| ≤ 100, mmHg | 2(10) |
| 101-200, mmHg | 2(10) |
| 201-300, mmHg | 5(25) |
| >300, mmHg | 11(55) |
| Blood count and biochemistry | |
| Haemoglobin, g/l | 12.8 (1.8) |
| Platelets, per 109/ L | 278(135) |
| White blood cells, per 109/ L | 9.3 (5.9) |
| Neutrophils, per 109/ L | 7.1 (5.7) |
| Lymphocytes, per 109/ L | 1.4 (0.7) |
| D-dimer, mg/L FEU | 2887 (4126) |
| Troponin T, ng/l | 62(158) |
| Radiological pattern, n (%) | |
| Interstitial | 20(100) |
| Bilateral ground glass opacities | 15(75) |
| Parenchymal consolidations | 9(45) |
| Comorbidities, n (%) | |
| Cardiovascular diseases | |
| Any cardiovascular disease | 12(60) |
| Hypertension | 8(40) |
| Ischaemic heart disease | 3(15) |
| Heart failure | 1(5) |
| Other | |
| Asthma | 3(15) |
| Diabetes mellitus | 2(10) |
| COPD | 1(5) |
| Active solid cancer | 1(5) |
| In-hospital treatment, n (%) | |
| LMWH | 18(90) |
| Antibiotics | 14(70) |
| O2 therapy | 14(70) |
| Corticosteroids | 13(65) |
| CPAP | 10(50) |
| Hydroxychloroquine | 10(50) |
| Lopinavir/ritonavir | 9(45) |
| Tocilizumab | 3(15) |
BMI, body mass index; COPD, chronic obstructive pulmonary disease; CPAP, continuous positive airway pressure; FEU, fibrinogen equivalent units; LMWH, low molecular weight heparin; SpO2, peripheral oxygen saturation; PaO2, partial arterial pressure of oxygen; PaCO2, partial arterial pressure of carbon monoxide; PaO2/FiO2, ratio between PaO2 and fraction of inspired oxygen.