Table 5.

Multivariate analyses comparing CFS, mCFS-1, and mCFS-2 against incident mortality and institutionalisation

Frailty category		Mortality			Institutionalisation or mortalityb
		Initial hospitalisation (n = 201)	6 months (n = 201)	12 months (n = 201)	Initial hospitalisation (n = 201)	6 months (n = 197)c	12 months (n = 197)c
		Adjusted OR (95% CI)			Adjusted OR (95% CI)
Clinical Frailty Scale (CFS)	5	–a	Ref	Ref	–a	Ref	Ref
	6	Ref	4.30 (1.20–15.46)*	3.90 (1.36–11.16)*	Ref	4.59 (1.49–14.11)*	4.83 (1.84–12.67)*
	7–8	2.16 (0.46–10.14)	14.08 (3.56–55.80)†	16.35 (4.85–55.10)†	1.05 (0.26–4.27)	13.23 (3.80–46.05)†	15.16 (4.80–47.91)†
		Adjusted OR (95% CI)			Adjusted OR (95% CI)
Modified CFS Version 1 (mCFS-1)	5	–a	Ref	Ref	–a	Ref	Ref
	6A 6B 7–8	Ref 2.39 (0.24–23.93) 3.97 (0.38–42.12)	1.64 (0.34–7.92) 7.13 (1.90–26.83)* 14.57 (3.66–57.96)†	1.83 (0.52–6.48) 6.33 (2.07–19.33)* 17.03 (5.02–57.84)†	Ref 0.68 (0.17–2.77) 0.85 (0.18–4.14)	3.27 (0.92–11.57) 5.85 (1.79–19.10)* 13.47 (3.86–46.97)†	3.55 (1.19–10.52)* 6.16 (2.19–17.38)* 15.51 (4.89–49.19)†
		Adjusted OR (95% CI)			Adjusted OR (95% CI)
Modified CFS Version 2 (mCFS-2)	5	–a	Ref	Ref	–a	Ref	Ref
	6A	Ref	1.64 (0.34–7.91)	1.83 (0.52–6.47)	Ref	3.26 (0.92–11.55)	3.54 (1.19–10.51)*
	6B1	1.54 (0.09–27.81)	5.16 (1.05–25.50)*	5.19 (1.30–20.69)*	0.33 (0.03–3.17)	3.89 (0.89–16.92)	5.44 (1.51–19.57)*
	6B2	2.94 (0.27–32.17)	8.18 (2.08–32.18)*	6.92 (2.14–22.35)*	0.95 (0.21–4.25)	6.99 (2.04–23.98)*	6.55 (2.19–19.63)*
	7–8	3.98 (0.38–42.37)	14.46 (3.64–57.42)†	16.93 (4.99–57.44)†	0.86 (0.17–4.20)	13.39 (3.84–46.64)†	15.47 (4.88–49.03)†

CFS Clinical Frailty Scale, CI confidence interval, OR odds ratio, Ref reference

Adjusted for age, gender, comorbidities, and severity of illness

^aNo case of mortality or institutionalisation in CFS category 5 at initial hospitalization

*p < 0.05

^†p < 0.001

^bParticipants who died during the specified period were counted as a case

^c4 patients excluded from 6- and 12q-month analyses due to loss to follow-up