Table 1.
Summary of time to recurrence and location of deposits for 18 cases of granular corneal dystrophy following deep anterior lamellar keratoplasty reported in the literature.
| Case Series | N | Surgical technique | Mean time to documented recurrence (range) | Location of deposits |
|---|---|---|---|---|
| Lewis et al. (2017)7 | 4 | Anwar big bubble and manual dissection | 1.2 years | Central basal epithelium and anterior stroma (N = 3). Posterior graft-host interface (manual dissection N = 1) |
| Avadhanam et al. (2016)15 | 3 | Unspecified | 5.4 (3–8.5) years | Preferentially in graft-host interface and along suture tracts and arcuate incisions (Posterior graft-host interface pattern not explicitly shown) |
| Scorcia et al. (2015)19 | 1 | Big bubble | 48 months | Unspecified; presumably, within DALK donor tissue that was replaced with DALK graft exchange |
| Pantanelli et al. (2014)5 | 1 | Melles manual dissection | 3 years | Host stroma anterior to Descemet membrane |
| Rama et al.(2013)6 | 1 | Unspecified | 6 months | Posterior graft-host interface |
| Unal et al. (2013)2 | 2 | Anwar big bubble or manual dissection | 14 months (N = 1) | Unspecified |
| Salouti et al. (2009)14 | 5 | Melles manual dissection | 15.6 ± 1.8 (13-16) months | Early – along suture tracts and peripheral graft-host junction. Late – superficial subepithelial area, peripheral stroma extending centrally |
| Park et al. (2007)20 | 1 | Unspecified | 13 months | Periphery adjacent to the graft-host junction |
N = number of documented recurrence events.