Table 2.
Characteristics of individuals with pulmonary function in normal, impaired fasting glucose, and type 2 diabetic subjects
Normal, n = 1608 | IFG, n = 934 | T2DM, n = 288 | |
Age (yr)1 | 53.63 ± 0.31a | 56.23 ± 0.40b | 58.95 ± 0.71c |
Male (%)1 | 42.9 ± 1.3a | 58.2 ± 1.7b | 62.0 ± 3.5b |
RPD/OPD (%)1 | 6.2/11.5a | 8.4/13.3b | 18.1/15.9c |
HOMA-IR1 | 1.45 ± 0.03a | 2.49 ± 0.06b | 5.52 ± 0.58c |
HOMA-beta1 | 84.75 ± 1.58a | 76.38 ± 1.93b | 48.56 ± 3.96c |
HbA1c (%)1 | 5.47 ± 0.01a | 5.79 ± 0.02b | 7.61 ± 0.12c |
Hs-CRP (mg/L)1 | 0.94 ± 0.04a | 1.34 ± 0.09b | 2.04 ± 0.30c |
Fasting insulin (UIU/mL)1 | 6.42 ± 0.12a | 9.35 ± 0.24b | 13.02 ± 1.05c |
BMI (kg/m2)1 | 23.63 ± 0.08a | 24.97 ± 0.11b | 25.19 ± 0.22b |
Fasting glucose (mg/dL)1 | 90.84 ± 0.16a | 107.44 ± 0.26b | 168.79 ± 3.34c |
Waist circumference (cm)1 | 81.52 ± 0.24a | 86.44 ± 0.31b | 88.32 ± 0.57c |
SBP (mmHg)1 | 117.92 ± 0.46a | 123.00 ± 0.58b | 126.55 ± 1.14c |
DBP (mmHg)1 | 76.39 ± 0.32a | 78.18 ± 0.39b | 77.10 ± 0.75a |
Total cholesterol (mg/dL)1 | 196.00 ± 0.96a | 198.67 ± 1.46a | 186.82 ± 2.73b |
LDL-cholesterol (mg/dL)1 | 118.77 ± 0.91a | 120.50 ± 1.30a | 107.90 ± 2.26b |
HDL-cholesterol (mg/dL)1 | 51.71 ± 0.39a | 48.25 ± 0.46b | 45.30 ± 0.72c |
Triglyceride (mg/dL)1 | 130.65 ± 3.08a | 166.09 ± 5.44b | 216.02 ± 15.20c |
Smoking status (%) (non-/ex-/current smoker)1 | 59.9/22.1/18.0a | 46.6/32.0/21.4b | 45.6/31.7/22.8b |
Drinking alcohol status (%) (non-/current drinking) | 26.4/73.6 | 23.6/76.4 | 28.9/71.1 |
FVC (% predicted)1 | 3.61 ± 0.26a | 3.72 ± 0.04b | 3.56 ± 0.07a |
FEV1 (L)1 | 2.81 ± 0.02a | 2.86 ± 0.03ab | 2.72 ± 0.05ac |
FEV1/FVC1 | 0.78 ± 0.00a | 0.77 ± 0.00b | 0.77 ± 0.01b |
PEF (L/sec)1 | 7.42 ± 0.06a | 7.73 ± 0.09b | 7.48 ± 0.15ab |
P < 0.05 by ANOVA or chi-square test. a,b,cThe same letters indicate non-significant difference between groups based on Bonferroni multiple comparison test. Data were presented as means ± SD or n (%). IFG: Impaired fasting glucose; T2DM: Type 2 diabetes mellitus; Hs-CRP: Hs-C-reactive protein; BMI: Body mass index; SBP: Systolic blood pressure; DBP: Diastolic blood pressure; LDL-cholesterol: Low density lipoprotein-cholesterol; HDL-cholesterol: High density lipoprotein-cholesterol; FVC: Forced vital capacity; FEV1: Forced expiratory volume 1.