Table 1. Baseline Patient Characteristics.
| Variables | Individuals, No. (%) | Standardized mean differencesc | |
|---|---|---|---|
| Without HPV (n = 76 088)a | With HPV (n = 76 088)b | ||
| Age, y | |||
| <20 | 21 426 (28.2) | 21 802 (28.7) | 0.01 |
| 20-49 | 39 448 (51.9) | 39 075 (51.4) | 0.01 |
| 50-64 | 9484 (12.5) | 9423 (12.4) | 0.002 |
| ≥65 | 5730 (7.5) | 5788 (7.6) | 0.003 |
| Mean (SD) | 33.7 (18.8) | 33.5 (18.8) | 0.01 |
| Sex | |||
| Women | 39 914 (52.5) | 39 738 (52.2) | 0.01 |
| Men | 36 174 (47.5) | 36 350 (47.8) | 0.01 |
| Comorbidity | |||
| Hypertension | 10 194 (13.4) | 10 285 (13.5) | 0.004 |
| Diabetes | 1991 (2.62) | 1918 (2.52) | 0.01 |
| Hyperlipidemia | 8297 (10.9) | 8643 (11.4) | 0.01 |
| Coronary artery disease | 5476 (7.20) | 5634 (7.40) | 0.01 |
| Cerebrovascular disease | 854 (1.12) | 834 (1.10) | 0.003 |
| Chronic kidney disease | 545 (0.72) | 526 (0.69) | 0.003 |
| COPD | 5022 (6.60) | 5169 (6.79) | 0.01 |
| Chronic liver diseases | 6791 (8.93) | 7120 (9.36) | 0.02 |
| Systemic lupus erythematosus | 43 (0.06) | 73 (0.10) | 0.01 |
| Ankylosing spondylitis | 270 (0.35) | 241 (0.32) | 0.01 |
| Rheumatoid arthritis | 78 (0.10) | 95 (0.12) | 0.01 |
| Sjögren syndrome | 24 (0.03) | 44 (0.06) | 0.01 |
| Hepatitis C | 654 (0.86) | 612 (0.80) | 0.006 |
| HIV | 45 (0.06) | 52 (0.07) | 0.004 |
| Hepatitis B | 2289 (3.01) | 2355 (3.10) | 0.005 |
| Comedications | |||
| Statin | 3161 (4.2) | 3236 (4.3) | 0.01 |
| NSAID | 42 194 (55.5) | 47 525 (62.5) | 0.14 |
| Antihypertensive drug | 12 672 (16.7) | 12 757 (16.8) | 0.003 |
Abbreviations: COPD, chronic obstructive pulmonary disease; HPV, human papillomavirus; NSAID, nonsteroidal anti-inflammatory drug.
a
Mean (SD) follow-up time, 7.14 (3.62) years.
b
Mean (SD) follow-up time, 7.29 (3.61) years.
c
A standardized mean difference of 0.1 or less indicates an insignificant difference.