Table 6.
Antimicrobial resistance phenotypes of 167 European V. cholerae O1 El Tor isolates, according to their phylogenetic grouping.
| Sublineage | Genomic wavea | AMR phenotypesb (number of isolates) |
|---|---|---|
| EUR1/AFR1 | 1 | PB, CS (20) |
| STR (1) | ||
| EUR2/AFR3 | 1 | PB, CS (1) |
| EUR3/AFR4 | 1 | PB, CS (3) |
| Pan-susceptible (1) | ||
| EUR4/AFR6 | 2 | PB, CS (35) |
| Pan-susceptible (9) | ||
| CS (1) | ||
| STR (1) | ||
| EUR5 | 2 | STR, SUL, FUR, PB, CS (16) |
| STR, SUL, PB, CS (2) | ||
| FUR, PB, CS (2) | ||
| STR, SUL (2) | ||
| STR, SUL, FUR (1) | ||
| STR, FUR, PB, CS (1) | ||
| STR, SUL, FUR, CS (1) | ||
| EUR6/AFR8 | 2 | STR, SUL, O129, SXT, TET, FUR, PB, CS (22) |
| STR, SUL, O129, SXT, FUR, PB, CS (9) | ||
| STR, SUL, O129, SXT, CHL, TET, FUR, PB, CS (8) | ||
| STR, SUL, O129, SXT, FUR (2) | ||
| STR, SUL, O129, SXT, PB, CS (2) | ||
| STR, SUL, O129, SXT, CS (1) | ||
| STR, SUL, O129, SXT (1) | ||
| STR, SUL, O129, SXT, TET, FUR (1) | ||
| STR, SUL, O129, SXT, TET, FUR, CS (1) | ||
| EUR7 | 3 | STR, SUL, O129, SXT, FUR, NAL, PB, CS (10) |
| STR, SUL, O129, SXT, CHL, FUR, NAL, PB, CS (4) | ||
| STR, SUL, O129, SXT, FUR, PB, CS (3) | ||
| STR, SUL, O129, SXT, CHL, FUR, PB, CS (2) | ||
| O129, FUR, NAL (1) | ||
| STR, SUL, O129, SXT (1) | ||
| STR, SUL, O129, SXT, FUR, NAL, CS (1) | ||
| STR, SUL, O129, SXT, NAL (1) |
CHL chloramphenicol, CS colistin, FUR furazolidone, NAL nalidixic acid, PB polymyxin B, STR streptomycin, SUL sulfonamides, SXT trimethoprim-sulfamethoxazole, O129 vibriostatic agent O/129, TET tetracycline.
aAccording to Mutreja et al.8.
bAMR antimicrobial resistance, Intermediate resistance (I), and resistance (R) have been grouped together to define the AMR phenotypes.