Figure 7:

Eosinophilic solid and cystic (ESC) renal cell carcinoma associated with liver metastasis (ESC #5, 15 year old female). The neoplasm demonstrates the typical features of ESC RCC, in that it demonstrates sheets of polygonal cells with eosinophilic cytoplasm focally lining cysts (A). On high power examination, the cytoplasm demonstrates the characteristic flocculent, clumped appearance (B). This patient developed liver metastases (C, note the native liver to the leftof the figure) which were partially cystic (D).