Table 2:
SDH-Deficient RCC
| Case | Age/Sex | Size/Stage | Notable pathologic features | Clinical history |
|---|---|---|---|---|
| SDH #1 | 21/F | 6 cm pT1Nx |
Nested, vacuolated cytoplasm, rare inclusions | NED x 61 months, no h/o neoplasia or genetic syndrome |
| SDH #2 | 17/M | 9.1 cm pT2Nx |
Tubular with focal papillary architecture. Called oncocytoma on frozen section. |
Presented with hypertension. No f/u available |
| SDH #3 | 20/M | 7.4 cm pT2Nx |
Vacuolated with inclusions | No f/u available |
| SDH #4 | 19/M | Size unknown | Nested with vacuolated cytoplasm and rare inclusions | NED x 11 months, no h/o neoplasia or genetic syndrome |
| SDH #5 | 31/M | 15 cm pT2N0 |
Pleomorphic, vacuolated, t(6:11)-like | No f/u available |
| SDH #6 | 17/M | 6.5 cm pT1Nx |
t(6;11)-like | Presented with hematuria. No f/u available |
| SDH #7 | 22/F | 9.0 cm pT2Nx |
Vacuolated cytoplasm | No f/u available |
| SDH #8 | 34/M | 10 cm pT2NxMx |
Pleomorphic with necrosis | T12 bone metastasis at diagnosis |
f/u= follow-up; h/o= history of; NED= no evidence of disease