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. Author manuscript; available in PMC: 2021 Mar 1.

Published in final edited form as: Int J Audiol. 2019 Nov 18;59(3):219–223. doi: 10.1080/14992027.2019.1690170

Table 4.

Covariates associated with hearing loss in 102 participants on treatment with kanamycin for multidrug-resistant tuberculosis

Variable	Univariate		Multivariate
Variable	HR (95%CI)	P value	aHR (95%CI)	P value
Sex	0.99 (0.64 to 1.53)	0.968
Age	0.98 (0.96 to 1.00)	0.058	0.97 (0.95 to 1.00)	0.050
HIV	1.06 (0.67 to 1.67)	0.813
Previous MDR-TB treatment	0.90 (0.56 to 1.45)	0.670
AUC_0–10 (per 10 μg•hr/L increase)	1.03 (1.00 to 1.05)	0.051	1.03 (1.00 to 1.06)	0.028

aHR: adjusted Hazard Ratio

HR: Hazard ratio

CI: Confidence Interval