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. 2020 Sep 29;21(19):7182. doi: 10.3390/ijms21197182

Figure 1.

Figure 1

Schematic overview of lysine acetylation and deacetylation. Lysine acetylation, which is catalyzed by KATs, involves transfer of an acetyl group from Ac-CoA to the ε-amino side chain of lysine or occurs nonenzymatically. Deacetylation of lysine residues is catalyzed by Zn2+-dependent HDACs or by NAD+-dependent SIRTs. NAD+, nicotinamide adenine dinucleotide.