53BP1 |
TP53-binding protein 1 |
6-4PPs |
6-4 photoproducts |
8-AIA |
8-(5-aminoimidazol-4-yl)adenine |
8-HDF |
8-hydroxy-5-deazaflavin |
AEJ |
Alternative end-joining |
AMD1 |
S-adenosylmethionine decarboxylase proenzyme |
AMP |
Adenosine monophosphate |
ANP32E |
Acidic leucine-rich nuclear phosphoprotein 32 family member E |
ANP32E |
Acidic leucine-rich nuclear phosphoprotein 32 family member E |
AP1/2 |
Activating protein 1/2 |
APE |
AP-endonulcease |
aPKCs |
Atypical protein kinase C |
APLF |
Aprataxin and PNK-like factor |
APTX |
Aprataxin |
ATM |
Ataxia telangiectasia mutated |
ATR |
Ataxia telangiectasia and Rad3-related protein |
ATRIP |
ATR-interacting protein |
BAK |
Bcl-2 homologous antagonist/killer |
BAX |
Apoptosis regulator BAX |
BCL2 |
Apoptosis regulator BCL2 |
BER |
Base excision repair |
BIRC3 |
Baculoviral IAP repeat-containing protein 3 |
BLM |
Bloom syndrome protein |
BRCA1 |
Breast cancer type 1 susceptibility protein |
BSC |
Basal cell carcinoma |
BTG1 |
BTG anti-proliferation factor 1 |
CAF-1 |
Chromatin assembly factor 1 |
CAT |
Catalase |
CCNG1 |
Cyclin G1 |
CDC25A/C |
M-phase inducer phosphatases |
CDKs |
Cyclin dependent kinases |
CDT1 |
DNA replication factor Cdt1 |
CENT2 |
Centrin 2 |
CHK1/2 |
Serine/threonine-protein kinase CHK1/2 |
Cho |
Excinuclease Cho |
COFS |
Cerebro-oculo-facioskeletal syndrome |
COP9 |
Constitutive photomorphogenesis 9 |
CPDs |
Cyclobutane-pyrimidine dimers |
CS |
Cockayne syndrome |
CSA/B |
Cockayne syndrome protein A/B |
CSN |
Constitutive photomorphogenesis 9 (COP9) signalosome |
CtlP |
CtBP-interacting protein |
DDB2 |
Damaged DNA-binding protein 2 |
DDR |
DNA damage response |
DDR1 |
Epithelial discoidin domain-containing receptor 1 |
DGPY |
4,6-diamino-5-guanidinopyrimidine |
DNA2 |
DNA replication ATP-dependent helicase/nuclease DNA2 |
DNA-PKcs |
DNA-dependent protein kinase catalytic subunit |
DP1 |
Transcription factor Dp-1 |
DR |
Direct reversal of damage |
dRP |
5’ deoxyribosephosphate |
DSBR |
Double strand break repair |
DSBs |
Double strand breaks |
DUSP5 |
Dual specificity protein phosphatase 5 |
EGFR |
Epidermal growth factor receptor |
ERKs |
Extracellular signal-regulated kinases |
EXO1 |
Exonuclease 1 |
FACT |
Facilitates chromatin transcription |
FADH |
Reduced flavin adenine dinucleotide |
FEN-1 |
Flap endonuclease 1 |
GADD45 |
Growth arrest and DNA damage-inducible protein GADD45 alpha |
GG-NER |
Global genomic NER |
GPX |
Glutathione peroxidase |
GR |
Glutathione reductase |
HIRA |
Histone regulator A |
HMGN1 |
High mobility group nucleosome−binding domain−containing protein 1 |
HR |
Homologous recombination |
IER3 |
Radiation-inducible immediate-early gene IEX-1 |
INO80 |
Chromatin-remodeling ATPase |
JNKs |
C-Jun NH2-terminal kinases |
KAP1 |
Nuclear corepressor KAP-1 |
KU70/80 |
X-ray repair cross-complementing protein 5/6 |
MAPK |
Mitogen-activated protein kinase |
MCM6 |
Minichromosome maintenance complex component 6 |
MCM7 |
DNA replication licensing factor 7 |
MDC1 |
Mediator of DNA damage checkpoint protein 1 |
MDM2 |
E3 ubiquitin-protein ligase MDM2 |
MM |
Malignant melanoma |
MMEJ |
Microhomology-mediated end-joining |
MRN |
MRE11-RAD50-NBS1 complexes |
mtDNA |
Mitochondrial DNA |
MTHF |
5,10-methyl tetrahydrofolate |
NAD+ |
Nicotinamide adenine dinucleotide |
NBS1 |
Nibrin |
NER |
Nucleotide excision repair |
NFAT |
Nuclear factor of activated T cells |
NFκB |
Nuclear factor kappa B |
NHEJ |
Non-homologous end joining |
NOLC1 |
Nucleolar and coiled-body phosphoprotein 1 |
ODC |
Ornithine decarboxylase |
P21 |
Cyclin-dependent kinase inhibitor 1A |
PAR |
Poly-ADP-ribose |
PARG |
Poly (ADP-ribose) glycohydrolase |
PARPs |
Poly [ADP-ribose] polymerases |
PCNA |
Proliferating cell nuclear antigen |
PEA15 |
Astrocytic Phosphoprotein PEA-15 |
PI3K |
Phosphoinositide 3-kinase |
Pol |
Polymerase |
POLE3 |
DNA polymerase epsilon subunit 3 |
pRB |
Retinoblastoma-associated protein |
PTMA |
Prothymosin alpha |
PUMA |
Bcl-2-binding component 3 |
RBX |
Ubiquitin-protein ligase RBX1 |
RAD23B |
UV excision repair protein RAD23 homolog B |
RAD51 |
DNA repair protein RAD51 |
RAD9-RAD1-HUS1 |
Cell cycle checkpoint control protein complex |
RARRES |
Retinoic acid receptor responder 1 |
RecA |
Recombinase A |
RFC |
Replication factor C |
RNAPII |
RNA polymerase II |
RNF8/20/40/168 |
E3 ubiquitin-protein ligases RNF8/20/40/168 |
ROS |
Reactive oxygen species |
RPA |
Replication protein A |
RUNX3 |
RUNX family transcription factor 3 |
S100A11 |
S100 calcium binding protein A11 |
SCC |
Squamous cell carcinoma |
SOD |
Superoxide dismutase |
SRM |
Spermidine synthase |
SSBR |
Single strand break repair |
SSBs |
Single strand breaks |
ssDNA |
Single strand DNA |
STATs |
Signal transducers and activators of transcription |
SWI/SNF |
Chromatin remodeling complexes |
TAX1BP1 |
Tax1-binding protein 1 |
TC-NER |
Transcription-coupled NER |
TDP-1 |
Tyrosyl-DNA phosphodiesterase 1 |
TF |
Transcription factor |
TFIIH |
Transcription factor II |
TLS |
Translesion synthesis |
TNF-α |
Tumor necrosis factor α |
TOB1 |
Transducer of erbB-2 1 |
TOPBP1 |
DNA topoisomerase 2-binding protein 1 |
TP53 |
Cellular tumor antigen p53 |
TRAF1 |
TNF receptor-associated factor 1 |
TRCF |
Transcriptional-repair coupling factor |
TRX |
Thioredoxin reductase |
TTD |
Trichothiodystrophy |
USP7 |
Ubiquitin−specific−processing protease 7 |
TTDA |
General transcription factor 2H subunit 5 |
TTDN1 |
Trichothiodystrophy non-phothosensitive 1 |
UVDE |
UV damage endonuclease |
UVER/UVDR |
UVDE-mediated excision repair |
UvrA/B/C |
UvrABC system protein |
UV-SS |
UV-sensitive syndrome |
WRN |
Werner syndrome ATP-dependent helicase |
XAB2 |
XPA−binding protein 2 |
XLF |
Cernunos |
XP |
Xeroderma pigmentosum |
XPC |
Xeroderma pigmentosum group C |
XRCC1/4 |
X-ray repair cross-complementing protein 1/4 |