Table 1.
Hematological and biochemical analysis of the Sprague-Dawley rats 14 days after treatment.
Parameter (Units) 2 | Group 1 | |||
---|---|---|---|---|
Normal | FO100 | FO200 | rhGH | |
RBC (106/μL) | 6.83 ± 0.42 | 6.77 ± 0.40 | 6.81 ± 0.37 | 6.84 ± 0.33 |
WBC (103/μL) | 3.44 ± 0.38 | 3.52 ± 0.59 | 3.68 ± 0.64 | 3.15 ± 0.76 |
Hematocrit (%) | 50.11 ± 2.32 | 49.74 ± 2.08 | 51.00 ± 1.93 | 49.93 ± 2.15 |
Hemoglobin (g/dL) | 14.55 ± 0.74 | 14.36 ± 0.49 | 14.64 ± 0.63 | 14.37 ± 0.58 |
MCV (fL) | 72.68 ± 1.83 | 72.33 ± 1.54 | 73.41 ± 1.92 | 73.51 ± 1.75 |
MCH (pg) | 21.42 ± 0.53 | 21.04 ± 0.44 | 20.79 ± 0.67 | 21.28 ± 0.53 |
MCHC (g/dL) | 28.97 ± 0.36 | 28.35 ± 0.42 | 28.75 ± 0.39 | 28.72 ± 0.35 |
Platelet (103/μL) | 1217.49 ± 236.81 | 1334.52 ± 201.57 | 1294.63 ± 194.68 | 1315.44 ± 186.37 |
ALT (U/L) | 13.72 ± 1.02 | 13.44 ± 0.85 | 12.96 ± 0.78 | 13.35 ± 0.89 |
AST (U/L) | 24.38 ± 2.72 | 21.06 ± 2.47 | 22.41 ± 3.11 | 20.85 ± 3.26 |
BUN (mg/dL) | 19.15 ± 2.34 | 20.27 ± 2.75 | 18.89 ± 3.06 | 18.12 ± 2.51 |
Creatinine (mg/dL) | 0.29 ± 0.04 | 0.29 ± 0.04 | 0.29 ± 0.02 | 0.28 ± 0.04 |
Calcium (mg/dL) | 12.84 ± 0.65 | 12.37 ± 0.39 | 12.27 ± 0.41 | 12.33 ± 0.43 |
Results are expressed as means ± SD of eight rats in each group. 1 Normal distilled water was orally administered; FO100, 100 mg/kg/day of fermented oyster (FO) extract was orally administered; FO200, 200 mg/kg/day of FO was orally administered; rhGH, 200 μg/kg/day of recombinant human growth hormone (rhGH) was subcutaneously injected. 2 RBC, red blood cells; WBC, white blood cells; MCV, mean corpuscular volume; MCH, mean corpuscular hemoglobin; MCHC, MCH concentration; ALT, alanine aminotransferase; AST, aspartate aminotransferase; BUN, blood urea nitrogen.