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. 2020 Oct 2;21(19):7300. doi: 10.3390/ijms21197300

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Scheme 1 — Adenosine and related metabolites together with their converting enzymes. AMP, adenosine monophosphate; ecto-5′NT (CD73), ecto-5′-nucleotidase; ADA, adenosine deaminase; PNP, purine nucleoside phosphorylase; XO, xanthine oxidase; GMP, guanosine monophosphate; HGPRT, hypoxanthine-guanine phosphoribosyltransferase; IMP, inosine monophosphate; AMPK, adenosine-monophosphate-activated protein kinase; PKA, cAMP-dependent protein kinase; ADK, adenosine kinase; SAHH, S-adenosylhomocysteine hydrolase; ENT, equilibrative nucleoside transporter; CNT, concentrative nucleoside transporter 2; AC, adenylyl cyclase.