AICD | Activation-induced Cell death |
APC | Antigen-presenting cell |
B-ALL | B-cell Acute Lymphoblastic Leukemia |
BCR | B-cell receptor |
BTLA | B- and T-lymphocyte attenuator |
CAR | Chimeric antigen receptor |
CRS | Cytokine release syndrome |
Csk | C-terminal Src kinase |
CTLA-4 | Cytotoxic T-lymphocyte-associated protein 4 |
Cryo-EM | Cryogenic electron microscopy |
DAP EC |
DNAX-activating protein Extracellular |
ERK EGFR GADS |
Extracellular signal-regulated kinase Epidermal growth factor receptor GRB2-related adaptor protein 2 |
Grb2 | Growth factor receptor-bound protein 2 |
HVEM | Herpes virus entry mediator |
ICOS | Inducible T-cell costimulatory |
IgSF | Immunoglobulin superfamily |
IS | Immune Synapse |
ITAM | Immunoreceptor tyrosine-based activation motif |
Itk | Interleukin-2-inducible T-cell kinase |
JAK | Janus kinase |
KIR | Killer Ig-like receptor |
KIR2DS2 Lck |
Killer Ig-like receptor two Ig domains and short cytoplasmic tail 2 Lymphocyte-specific protein tyrosine kinase |
MHC | Major histocompatibility complex |
NK NKG2D |
Natural killer Natural killer group 2 member D |
pMHC | Peptide-bound major histocompatibility complex |
PDB LFA-1 |
Protein Data Bank Lymphocyte function-associated antigen 1 |
NMR | Nuclear Magnetic Resonance |
Nck | Non-catalytic region of tyrosine kinase adaptor protein 1 |
PD-1 PI3K |
Programmed death receptor 1 Phosphoinositide 3-kinase |
PKC | Protein kinase C |
scFv | Single-chain variable fragment |
SH2 SHP-1 |
Src-homology 2 Src homology 2 domain-containing protein tyrosine phosphatase 1 |
STAT | Signal Transducer and Activator of Transcription protein |
TCR | T cell receptor |
THEMIS TM |
Thymocyte-expressed-molecule Transmembrane |
TNF | Tumor necrosis factor |
TNFR TNFRSF TRAF |
Tumor necrosis factor receptor Tumor necrosis factor receptor Superfamily TNF receptor associated factor |
ZAP-70 | Zeta-associated protein 70 |