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. 2020 Oct 4;21(19):7337. doi: 10.3390/ijms21197337

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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The effects of Resv and ET on protein ubiquitination. Treatment with Resv or Resv with ET decreased protein ubiquitination, expressed as Ub1. Corresponding densitometry measurements: A, WT mice; B, 3xTg-AD mice; C, 3xTg-AD mice + ET; D, 3xTg-AD mice + Resv; E, 3xTg-AD mice + Resv + ET. AD, Alzheimer’s disease; ET, exercise training; Resv, resveratrol. Data presented as mean ± SD for 3 mice per group. *, compared to WT mice, p < 0.05; ^†, compared to 3xTg-AD mice, p < 0.05; ^‡, compared to 3xTg-AD mice + ET, p < 0.05.