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. 2020 Sep 29;21(19):7183. doi: 10.3390/ijms21197183

Figure 4.

Figure 4

Schematic presentation of the ternary complex model of MCPIP1. Based on the size exclusion chromatography results Wilamowski et al. proposed a sequential binding model: oligo  +  MCPIP1dimer  +  MCPIP1dimer ⇄ oligo-MCPIP1dimer  +  MCPIP1dimer ⇄ oligo-MCPIP1tetramer (MCPIP1 marked as a yelow box). MCPIP1 degrades RNA molecules as a tetramer [31].