Table 3.
Camk2b mutant mice.
| Name | Description | References |
|---|---|---|
| Camk2b−/− | Deletion exon 11 | [20] |
| Camk2b−/− | Deletion exon 2 | [31] |
| Camk2b−/− | Camk2bf/f (loxP sites flanking exons 7–8) crossed with a CMV-Cre mouse | [32] |
| Camk2bf/f | LoxP sites flanking exon 2 | [33] |
| Camk2bA303R/A303R | Mutant which cannot bind Ca2+/CaM (mutation prevents CaMKIIβ enzymatic activation, while preserving its ability to bind to actin) | [34] |
| Camk2bT287A/T287A | Autophosphorylation-deficient mutant (mutation blocks CaMKIIβ autonomous activity) | [33] |
| Camk2b exon 13:TS/A knock-in mouse | Mouse carrying phosphoblock mutations in the actin binding domain (phosphorylation sites of this region are critical for CaMKII detachment from F-actin) | [35] |
| Camk2a−/−;Camk2b −/− | Camk2a−/− [36] and Camk2b−/− [20] were used to generate double mutants | [37] |