Table 1.

Physiological parameters of the aorta and cardiac ventricles of wild-type (WT) and Marfan syndrome (MFS) mice obtained by ultrasound measurements at 3 months of age. Measurements of the aorta include 12 WT and 12 MFS mice. Measurements of the cardiac ventricles include 5 WT and 6 MFS mice. p-values were calculated using an independent samples test.

	WT	MFS	p-Value
Ao Diameters
Ao Sinus (mm)	1.61 ± 0.10	2.15 ± 0.09	0.001
Ao Asc (mm)	1.55 ± 0.10	2.89 ± 0.10	<0.001
Arch (mm)	1.43 ± 0.06	2.01 ± 0.06	<0.001
Ao Desc (mm)	1.15 ± 0.07	1.37 ± 0.06	0.038
LVESD (mm)	3.27 ± 0.08	3.24 ± 0.16	ns
LVEDD (mm)	4.20 ± 0.11	4.49 ± 0.17	ns
RVEDD (mm)	1.92 ± 0.10	2.11 ± 0.09	ns
LV FS (%)	22.14 ± 1.30	27.71 ± 2.88	ns
E (mm/s)	625.3 ± 54.2	310.5 ± 56.8	0.002
A (mm/s)	386.3 ± 36.5	382.0 ± 35.3	ns
E/A	1.67 ± 0.14	0.84 ± 0.14	0.002

WT, wild-type; MFS, Marfan syndrome; Ao, aorta; Ao Asc, ascending aorta; Ao Desc, descending aorta; LVESD, left ventricular end systolic diameter; LVEDD, left ventricular end diastolic diameter; RVEDD, right ventricular end diastolic diameter; LV FS, left ventricular fractional shortening; E, early left ventricular filling velocity; A, late left ventricular filling velocity; ns, not significant. Values are mean ± SE.