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Schematic representation of STAT1 and STAT3 domains. STATs structure is composed by N-domain (NTD), coiled-coil domain (CCD), DNA binding domain (DBD), linker domain (LD), Src homology 2 domain (SH2D) and transcriptional activation domain (TAD). Between SH2D and TAD there is a tail segment that contains the Tyrosine and Serine phosphorylation sites.
