Table 1.
Cytokines, growth factors and related JAKs involved in the activation of STAT1 and STAT3 signaling.
| Cytokines | JAKs | STATs |
|---|---|---|
| IFN-g | JAK1, JAK2 | STAT1 |
| NP | JAK1, (JAK2) | STAT3 |
| CT-1 | JAK1, (JAK2) | STAT3 |
| G-CSF | JAK1, (JAK2) | STAT3 |
| Leptin | JAK2 | STAT3 |
| GH | JAK2 | STAT3 |
| IFN-a/b | JAK1, TYK2 | STAT1/STAT3 |
| IL-6 | JAK1, (JAK2) | STAT1/STAT3 |
| IL-9 | JAK1, JAK3 | STAT1/STAT3 |
| IL-10 | JAK1, TYK2 | STAT1/STAT3 |
| IL-11 | JAK1 | STAT1/STAT3 |
| IL-12 | TYK2, JAK2 | STAT1/STAT3 |
| IL-19 | JAK1, JAK2 | STAT1/STAT3 |
| IL-20 | JAK1, JAK2 | STAT1/STAT3 |
| IL-21 | JAK1, JAK3 | STAT1/STAT3 |
| IL-22 | JAK1, TYK2 | STAT1/STAT3 |
| LIF | JAK1, (JAK2) | STAT1/STAT3 |
| CNTF | JAK1, (JAK2) | STAT1/STAT3 |
| OSM | JAK1, (JAK2) | STAT1/STAT3 |