Figure 9.

Doxorubicin cumulative release from PEGylated PHB nanoparticles measured in acid (squares) and blood plasma (trigons). Colored lines show the modeled release profiles as follows: red line draws the release kinetics in acid built from initial burst (yellow line), polymer degradation (green line) and diffusion (black line) in acid (A); blue line draws the release in blood plasma in the (B). In the insert (B), the measured data and the fitted release profiles can be seen on the whole time scale.