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. 2020 Oct 8;21(19):7421. doi: 10.3390/ijms21197421
OA osteoarthritis
H2S hydrogen sulfide
Nrf-2 nuclear factor-erythroid 2-related factor 2
PGs prostaglandins
MMPs metalloproteinases
COX-2 inducible isoform of cyclooxygenase
ROS reactive oxygen species
NO nitric oxide
iNOS inducible NO synthase
ECM extracellular matrix
C group under non-treatment
CI group treated with intraarticular injection of saline
SI group treated with intraarticular injection of H2S donor
MTP medial compartment from tibial plateau
MFC medial compartment from femoral condyl
8-oxo-dG 8-Hydroxy-2′-deoxyguanosine
4-HNE 4-hidroxi-2-nonenal
Nfe2l2 nrf-2 gene
Nqo1 NADPH:quinone oxidoreductase gene
Hmox1 heme oxygenase-1 gene
Tnf tumor necrosis factor-α gene
Ptgse COX-2 gene
Il1b interleukin-1β gene
Cxcl1 cytokine-induced neutrophil chemoattractant-1 gene
3-MPST 3-Mercaptopyruvate sulfurtransferase
CSE cystathionine γ-lyase
CBS cystathionine β-synthetase
MIA monosodium iodoacetate
NaSH sodium hydrosulfide
TNF-α tumor necrosis factor-α
NF-κB nuclear factor-κB
NQO1 NADPH:quinone oxidoreductase
HO-1 heme oxygenase-1
SEM standard error of the mean