Table 1.

Cellular processes affected by NS8593.

Cell Type/Tissue	Effects of NS8593	References
HEK293,	Motility/chemotaxis	[101]
primary microglia,		[110]
A172 glioblastoma cells		[111]
Primary ventricular myocytes,	Mg2+ homeostasis	[112,113]
primary vascular smooth muscle cells,		[114]
HT29 epithelial colon cells		[115]
Mouse oocytes and eggs,	Ca2+ uptake, intracellular Ca2+ stores and Ca2+ signalling	[41,116]
DT40 B lymphocytes,		[117]
primary enamel cells,		[118]
3T3-L1 fat cells		[119]
MDA-MB-231 breast cancer cells,	Proliferation/cell cycle	[120]
A172 glioblastoma cells		[111]
MDA-MB-468 breast cancer cells	Differentiation	[121]
Primary B cells,	Immune responses	[122]
mouse erythrocytes		[123]
primary microglia		[120]
primary macrophages		[110]
HuH7 hepatocellular carcinoma in a xenograft mouse model	Tumour growth	[74]
Kidneys	Fibrosis	[49]