ATM |
Ataxia telangiectasia mutated |
ATP |
Adenosine triphosphate |
ATR |
Ataxia telangiectasia and Rad3-related |
AR |
Androgen receptor |
BACK |
BTB and C-terminal Kelch |
BTB |
Bric-à-brac/Tramtrack/Broad complex |
BTBPs |
Bric-à-brac/Tramtrack/Broad complex (BTB) domain-containing proteins |
BRCA1 |
Breast cancer susceptibility gene 1 |
BRD |
Bromodomain containing |
ccRCC |
Clear-cell renal cell carcinoma |
ChK1 |
Checkpoint kinase 1 |
ChK2 |
Checkpoint kinase 2 |
CUL |
Cullin |
DNA |
Deoxyribonucleic acid |
DNA-PK |
DNA-dependent protein kinase |
DDR |
DNA damage response |
DSB |
Double-strand break |
HDR |
Homology-directed repair |
IR |
Ionizing irradiation |
LLPS |
Liquid-liquid phase separation |
MATH |
Meprin and TRAF-C homology |
MRE11 |
Meiotic recombination 11 |
MRN |
The Mre11-Rad50-Nbs1 |
mRNA |
Messenger ribonucleic acid |
NCOA3 |
Nuclear receptor coactivator 3 |
NHEJ |
Non-homologous end joining |
NLS |
Nuclear localization sequence |
PARP1 |
Poly[ADP-ribose] polymerase 1 |
PTEN |
Phosphatase and tensin homologue deleted on chromosome 10 |
RNA pol II |
RNA polymerase II |
ROS |
Reactive oxygen species |
RPA |
Replication protein A |
SB |
SPOP-binding |
SCID |
Severe combined immunodeficiency |
SPOP |
Speckle type BTB/POZ protein |
SSB |
Single-strand break |
TDP |
Tyrosyl-DNA phosphodiesterase |
TOP1 |
Topoisomerase 1 |
TOP2 |
Topoisomerase 2 |
TRIM24 |
Tripartite motif containing 24 |
Ub |
Ubiquitin |
UV |
Ultraviolet |
WGS |
Whole genome sequence |