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. 2020 Oct 7;21(19):7400. doi: 10.3390/ijms21197400

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Deregulated biological functions in KCNK3-knockdown hPASMCs and the protein network of interactions. (A) Heatmap representing the up-regulated (orange) or down-regulated (blue) biological functions in hPASMCs transfected with siKCNK3. (B) Histogram representing the 10 first deregulated biological functions in hPASMCs transfected with siKCNK3, classified according to –log (p-value). (C) Representation of the dysregulated network 1: RNA post-transcriptional modifications, cancer, and hematological disease. Red proteins are up-regulated proteins and green proteins are down-regulated proteins.