Table 1.
List of putative fusion genes selected by EricScript (white rows) and ChimeraScan (grey rows) tools, with the name of the partner genes, the estimated breakpoints, the type of fusions (e.g., Inter-chromosomal, Read Through) and a reliability score. + = sense or coding strand; - = antisense or not coding strand
| Fusion | Gene Name 5p | Gene Name 3p | chr 5p | Breakpoint 1 (End 5p) |
Strand 5p | chr 3p | Breakpoint 2 (Start 3p) | strand 3p | Fusiozn Type | JunctionSequence | Score |
|---|---|---|---|---|---|---|---|---|---|---|---|
| RNF123-STAT3 | RNF123 | STAT3 | 3 | 49,728,680 | + | 17 | 49,728,680 | - | inter-chr | ccgcaagagctataggctgacctcagatgctgagaaatccagggtcacagCTACTCGGGAGGCTGAGGCAGGAGAATCGCTTGAACCTGAGAGGCGGAGG | 0.91586235 |
| PLK1-ERN2 | PLK1 | ERN2 | 16 | 23,701,614 | + | 16 | 23,702,074 | - | Cis | gtgggttctacagccttgtccccctccccctcaaccccaccatatgaattGCTGGGTGCAGTGGCTCACACCTGTAATCCCAGCATTTTGGGAGGCTGAG | 0.690112004 |
| MRPS31-SUGT1 | MRPS31 | SUGT1 | 13 | 41,323,274 | - | 13 | 53,231,667 | + | intra-chr | gtggacaaaagaggggaaactatgggagttcccaattaacaatgaagcagGAGCTGACTAAGGCTTTGGAACAGAAACCAGATGATGCACAGTATTATTG | 0.734629203 |
| LPHN1-SUZ12 | LPHN1 | SUZ12 | 19 | 14,316,797 | - | 17 | 30,267,305 | + | inter-chr | cgagccgcaggagagacacgctgggccgaccccagagaggcgctggacagAGCCAACACAGATCTATAGATTTCTTCGAACTCGGAATCTCATAGCACCA | 0.855475528 |
| EIF5AL1-MSH3 | EIF5AL1 | MSH3 | 10 | 81,274,508 | + | 5 | 81,274,508 | + | inter-chr | aagactgtgaaaatgaatccagaggtgacccaagcattgaatttaacaatGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGTAGGCAGA | 0.532811583 |
| GUCY2C-PLBD1 | GUCY2C | PLBD1 | 12 | 14,765,813 | - | 12 | 14,721,126 | - | Read- Through |
accttccactctggaaccttattccagcagttgttccagggagcttctacCTGTGGAGGCCTCTCCAGAAACAGCAGAGGATCCGAGCTGCGTGTAGGCA | 0.896360711 |
| HSPE1-MOB4 | HSPE1 | MOB4 | 2 | 198,367,852 | + | 2 | 198,388,348 | + | Read- Through |
aagttcttctcccagaatatggaggcaccaaagtagttctagatgacaagGATTTCTATAATTGGCCTGATGAATCCTTTGATGAAATGGACAGTACACT | 0.821493951 |
| PDLIM2-CCAR2 | PDLIM2 | CCAR2 | 8 | 22,455,537 | + | 8 | 22,463,248 | + | intra-chr | agagattggctgtgggcctcagtttccccattttataaagttttaaaatctGCCTTTTCCCCACGACTCTGAAAGAGGACAGCGTTCCCAATGTCCCAGTTT | 5 |
| HPSE2-HSD11B2 | HPSE2 | HSD11B2 | 10 | 100,995,631 | - | 16 | 67,469,859 | + | inter-chr | tctcttcctactgggtctcgctagtgactaattgtccttatctaaagtgtgGGCCTGTGGGGCCTCGTCAACAACGCAGGCCACAATGAAGTAGTTGCTGAT | 2 |
| HDAC1-MARCKSL1 | HDAC1 | MARCKSL1 | 1 | 32,799,223 | + | 1 | 32,799,429 | - | Adjacent_ Converging |
agatactattttcatttttgtgagcctctttgtaataaaatggtacatttcTAAAGCACCACTAAAGGGACGACATTTATTCCTTTTCCAAATGTTACAGTA | 2 |
| ARSA-TNS4 | ARSA | TNS4 | 22 | 51,066,600 | - | 17 | 38,632,079 | - | inter-chr | gccggtaccgggctgcgggcgcttccgcctcggccccgccccgtgacctgtCTTACTGTTTTGCAAAGACAAACATTTTATTTTTCATGATAGGAGCTGTAG | 4 |
| ERBB2-MIEN1 | ERBB2 | MIEN1 | 17 | 37,883,255 | + | 17 | 37,885,408 | - | Adjacent_ Converging |
cccgggcgctgggggcatggtccaccacaggcaccgcagctcatctaccagATTAGTGTTTGTAGCGCCACTTTACTGCCAATAGCTGACATTGCCCTGGGT | 4 |