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. 2020 Sep 29;21(19):7181. doi: 10.3390/ijms21197181

Figure 2.

Figure 2

Cell viability, executioner 3/7 caspase activity, and Unfolded Protein Response (UPR) induction in SH-Syn. (A) Live cell count by Trypan blue staining of SH-Syn and SH-Mock. Data are presented as the means ± SD from three independent experiments, each performed in triplicate. Data were analyzed by a two-tailed Student’s t-test (* p < 0.05). (B) Analysis of caspase 3/7 activity in SH-Syn and SH-Mock. Data are presented as the means ± SD from two independent experiments, each performed in triplicate. Data were analyzed by a two-tailed Student’s t-test (* p < 0.05). (C) BiP (Binding immunoglobulin Protein), ATF4 (activating transcription factor 4), CHOP (C/EBP homologous protein), and r-XBP1 (the ratio between X-box binding protein 1′s unconventional spliced form and X-box binding protein 1′s unspliced form) mRNA quantification via qPCR in SH-Syn and SH-Mock. Data are presented as the mean ± SD of three independent experiments, each performed in duplicate. Data were analyzed by a Mann–Whitney Rank Sum Test (* p < 0.05).