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. 2020 Sep 29;21(19):7181. doi: 10.3390/ijms21197181
αSyn αSynuclein
αSyn-EN Endogenous Syn
αSyn-OE Overexpressed Syn
Amyloid-beta peptide
AD Alzheimer’s Disease
ATF4 Activating transcription factor 4
BiP Binding Immunoglobulin Protein
CHOP C/EBP homologous protein
CLU Clusterin
co-IP Co-immunoprecipitation
DAPI 4′dye-6˗diamidino˗2˗phenylindole
GAPDH Glyceraldehyde 3˗phosphate dehydrogenase
GWAS Genome-Wide Association Study
HMW High molecular weight
HSF-1 Heat shock factor-1
IB Immunoblotted
iCLU Intracellular CLU
IP Immunoprecipitated fraction
IRE1α Inositol-requiring enzyme 1 alpha
LB Lewy bodies
LN Lewy neuritis
MES Mesencephalic/neuroblastoma hybrid cell line
pCLU CLU precursor protein
PD Parkinson’s Disease
PERK PKR-like ER kinase
qPCR Quantitative real-time PCR
r-XBP1 XBP1us/XBP1
sCLU CLU secreted protein
SH-SY5Y Human neuroblastoma cell line
SH-Mock SH-SY5Y cells transfected with pHM6-mock
SH-MockT MG132 treated control cells
SH-Syn SH-SY5Y cells transfected with pHM6-αSyn-wt
SH-SynNC NC-transfected SH-Syn
SH-SynNC-T MG132 treated NC-transfected SH-Syn
SH-SynsiRNA CLU siRNA-transfected SH-Syn
SH-SynsiRNA-T MG132 treated CLU siRNA-transfected SH-Syn
SH-SynT MG132 treated SH-Syn
UPR Unfolded Protein Response
XBP1 X-box binding protein 1
XBP1us X-box binding protein 1 unconventional spliced form