αSyn |
αSynuclein |
αSyn-EN |
Endogenous Syn |
αSyn-OE |
Overexpressed Syn |
Aβ |
Amyloid-beta peptide |
AD |
Alzheimer’s Disease |
ATF4 |
Activating transcription factor 4 |
BiP |
Binding Immunoglobulin Protein |
CHOP |
C/EBP homologous protein |
CLU |
Clusterin |
co-IP |
Co-immunoprecipitation |
DAPI |
4′dye-6˗diamidino˗2˗phenylindole |
GAPDH |
Glyceraldehyde 3˗phosphate dehydrogenase |
GWAS |
Genome-Wide Association Study |
HMW |
High molecular weight |
HSF-1 |
Heat shock factor-1 |
IB |
Immunoblotted |
iCLU |
Intracellular CLU |
IP |
Immunoprecipitated fraction |
IRE1α |
Inositol-requiring enzyme 1 alpha |
LB |
Lewy bodies |
LN |
Lewy neuritis |
MES |
Mesencephalic/neuroblastoma hybrid cell line |
pCLU |
CLU precursor protein |
PD |
Parkinson’s Disease |
PERK |
PKR-like ER kinase |
qPCR |
Quantitative real-time PCR |
r-XBP1 |
XBP1us/XBP1 |
sCLU |
CLU secreted protein |
SH-SY5Y |
Human neuroblastoma cell line |
SH-Mock |
SH-SY5Y cells transfected with pHM6-mock |
SH-MockT
|
MG132 treated control cells |
SH-Syn |
SH-SY5Y cells transfected with pHM6-αSyn-wt |
SH-SynNC
|
NC-transfected SH-Syn |
SH-SynNC-T
|
MG132 treated NC-transfected SH-Syn |
SH-SynsiRNA
|
CLU siRNA-transfected SH-Syn |
SH-SynsiRNA-T
|
MG132 treated CLU siRNA-transfected SH-Syn |
SH-SynT
|
MG132 treated SH-Syn |
UPR |
Unfolded Protein Response |
XBP1 |
X-box binding protein 1 |
XBP1us |
X-box binding protein 1 unconventional spliced form |