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. 2020 Sep 30;21(19):7254. doi: 10.3390/ijms21197254

Figure 2.

Figure 2

Figure 2

Hypothetical mechanisms for Cox5a/bp incorporation into COX during transition from aerobic to anaerobic growth conditions. (A) Cox1p assembly under aerobic conditions. (B) Subunit Cox5a/bp switch using a hypothetical subunit isoform switch mechanism. (C) Hypothetical subunit degradation mechanism where Cox5ap is degraded to reform the earlier assembly intermediate which can then accept newly expressed Cox5bp. D1, D2, D3, D4 and D5 represent discrete Cox1p containing assembly intermediates. The asterisks (*) represent hypothetical assembly intermediates with altered subunits from the earlier assembly intermediate not marked with the asterisk.