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. 2020 Sep 23;25(19):4365. doi: 10.3390/molecules25194365

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© 2020 by the author.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Scheme 8 — Cu-mediated synthesis of 6-l-[¹⁸F]FDOPA using aryl trimetyl stannane as labeling precursor. R = Me, ¹⁸F/KOTf/K₂CO₃; Cu(OTf)₂, Py, 100 ^oC, 30 min, DMA [76]; R = Et; ¹⁸F/Et₄NOTf; Cu(OTf)₂Py₄; DMA; 100 °C, 10 min, air [86].