ACT |
adoptive cell-transfer |
APC |
antigen presenting cell |
APM |
antigen processing machinery |
ATF1 |
activating transcriptor factor 1 |
ATP |
adenosine triphosphate |
BiTES |
bi-specific T-cell engager antibodies |
BLS |
bare lymphocyte disease |
CAR |
chimeric antigen receptor |
CIITA |
class II trans-activator |
CIITA |
class I trans activator |
CLIP |
class II-associated I chain peptide |
CNX |
calnexin |
CREB1 |
cAMP-responsive element binding protein 1 |
CRT |
calreticulin |
CTL |
cytotoxic T lymphocyte |
CTLA-4 |
cytotoxic T-lymphocyte antigen 4 |
DC |
dendritic cell |
DFS |
disease free survival |
DNMTi |
DNA methyltransferase inhibitor |
EGFR |
epithelial growth factor receptor |
ER |
endoplasmic reticulum |
HDAC |
histone deacetylase |
HLA |
human leukocyte antigen |
ICI |
immune checkpoint inhibitor |
IFN |
interferon |
IRF |
IFN Regulatory Factor |
ISRE |
IFN-sensitive response element |
KIR |
killer cell immunoglobulin-like receptor |
JAK |
janus kinase |
LAG-3 |
lymphocyte activation gene 3 |
LMP |
low molecular weight protein |
LOH |
loss of heterozygosity |
mAb |
monoclonal antibody |
MAPK |
mitogen-activated protein kinase |
MEK |
MAPK/ERK kinase |
MHC |
major histocompatibility complex |
MIIC |
MHC class II compartment |
NF-kB |
nuclear factor kB |
NFY |
nuclear transcriptor factor Y |
NK |
natural killer |
NLRC5 |
NOD-like receptor 5 |
OS |
overall survival |
PD-1 |
programmed cell death 1 |
PD-L1 |
programmed cell death ligand 1 |
PFS |
progression free survival |
RFX |
regulatory factor X |
RFXANK |
RFX-associated ankyrin-containing protein |
RFXAP |
RFX associated protein |
TAP |
transporters associated with antigen processing |
TCR |
T-cell receptor |
TKI |
tyrosine kinase inhibitor |
TNF-α |
tumor necrosis factor alpha |
TA |
tumor antigen |
TAA |
tumor associated antigen |
TAM |
Type II tumour-associated macrophages |
TIL |
tumor-infiltrating lymphocyte |
TME |
tumor microenvironment |
Treg |
regulatory T cell |
TSA |
tumor specific antigen |
tsMHC-II |
tumor specific MHC class II |
β2-m |
β2-microglobulin |